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Our top choices for Southern Illinois hotels
Drury Inn & Suites Marion
Drury Inn & Suites MarionMarion
9.4 out of 10, Exceptional, (1,002 reviews)
"Clean room, great breakfast and evening drinks & food. Friendly staff."
Brandy
The price is AU$188
includes taxes & fees
12 July - 13 July
Suite Dreams Hotel
Suite Dreams HotelMattoon
8.8 out of 10, Excellent, (3 reviews)
"Owners are very nice and take pride in their hotel and it shows!"
Judd
The price is AU$129
includes taxes & fees
26 June - 27 June
The Principal Hotel
The Principal HotelColumbia
9.6 out of 10, Exceptional, (311 reviews)
"Great hotel and nice staff!"
Michelle
The price is AU$165
includes taxes & fees
24 June - 25 June
Hampton Inn & Suites Effingham
Hampton Inn & Suites EffinghamEffingham
9.6 out of 10, Exceptional, (742 reviews)
"Everything about this place was excellent"
Andrew
The price is AU$207
includes taxes & fees
19 July - 20 July
Holiday Inn Effingham by IHG
Holiday Inn Effingham by IHGEffingham
9.2 out of 10, Wonderful, (692 reviews)
"Nice hotel. Great location on the Ohio River. Walking distance to the old downtown."
Glenn
The price is AU$168
includes taxes & fees
2 July - 3 July
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Holiday Inn Express & Suites Murphysboro - Carbondale by IHGMurphysboro
9.4 out of 10, Exceptional, (553 reviews)
"Great place and folks!! Breakfast was on point, and the staff is very nice and friendly. Will be back!"
Mark
The price is AU$187
includes taxes & fees
28 June - 29 June
Country Inn & Suites by Radisson, Effingham, IL
Country Inn & Suites by Radisson, Effingham, ILEffingham
8.8 out of 10, Excellent, (1,004 reviews)
"Wonderful stay. "
Jennifer
The price is AU$151
includes taxes & fees
5 July - 6 July
Cobblestone Inn & Suites - Altamont
Cobblestone Inn & Suites - AltamontAltamont
9.6 out of 10, Exceptional, (880 reviews)
"The hotel was fabulous!"
Dominic
The price is AU$130
includes taxes & fees
25 June - 26 June
Charleston House Bed & Breakfast Inn
Charleston House Bed & Breakfast InnCharleston
10.0 out of 10, Exceptional, (12 reviews)
"The place was fantastic and just what I was looking for. The room was excellent, clean, comfortable. The host was great! Breakfast was delicious!
"
Kristy
The price is AU$134
includes taxes & fees
7 July - 8 July
La Quinta Inn & Suites by Wyndham Effingham
La Quinta Inn & Suites by Wyndham EffinghamEffingham
9.2 out of 10, Wonderful, (1,004 reviews)
"Clean hotel, excellent staff, good breakfast"
Alexis
The price is AU$171
includes taxes & fees
5 July - 6 July
Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. VernonMount Vernon
9.6 out of 10, Exceptional, (1,713 reviews)
"A nice stay"
DAVID
The price is AU$179
includes taxes & fees
12 July - 13 July
Fairfield by Marriott Inn & Suites Mattoon
Fairfield by Marriott Inn & Suites MattoonMattoon
8.4 out of 10, Very good, (12 reviews)
"The Belgium waffle's were excellent."
Stephen
The price is AU$227
includes taxes & fees
30 June - 1 July
Walker's Bluff Casino Resort
Walker's Bluff Casino ResortCarterville
9.4 out of 10, Exceptional, (469 reviews)
"Nice hotel!"
Monique
The price is AU$195
includes taxes & fees
29 June - 30 June
Ramada by Wyndham Effingham
Ramada by Wyndham EffinghamEffingham
7.4 out of 10, Good, (1,002 reviews)
"The staff is great, they do a really good job."
Martin
The price is AU$97
includes taxes & fees
12 July - 13 July
Comfort Suites Effingham Central
Comfort Suites Effingham CentralEffingham
8.8 out of 10, Excellent, (628 reviews)
"Clean, friendly staff, good breakfast. Recommend"
Paula
The price is AU$162
includes taxes & fees
6 July - 7 July
Holiday Inn Express & Suites Effingham by IHG
Holiday Inn Express & Suites Effingham by IHGEffingham
9.4 out of 10, Exceptional, (1,001 reviews)
"Breakfast was great!"
Carol
The price is AU$195
includes taxes & fees
3 July - 4 July
Days Inn & Suites by Wyndham Casey
Days Inn & Suites by Wyndham CaseyCasey
7.6 out of 10, Good, (889 reviews)
"Clean room and great staff!"
Beth
The price is AU$107
includes taxes & fees
28 June - 29 June
Quality Inn Effingham North
Quality Inn Effingham NorthEffingham
8.4 out of 10, Very good, (1,005 reviews)
"Nice overnight stay"
Suzanne
The price is AU$138
includes taxes & fees
5 July - 6 July
SureStay Hotel by Best Western Whittington Rend Lake
SureStay Hotel by Best Western Whittington Rend LakeWhittington
8.8 out of 10, Excellent, (983 reviews)
"Staff was friendly room was clean"
Brandon
The price is AU$136
includes taxes & fees
1 July - 2 July
Best Western Delta Inn
Best Western Delta InnEffingham
9.0 out of 10, Wonderful, (1,007 reviews)
"Nice quick stay"
Bri
The price is AU$160
includes taxes & fees
28 June - 29 June
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Photo by Southernmost Illinois Tourism Bureau
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Top Southern Illinois Hotel Reviews
Drury Inn & Suites St. Louis Fairview Heights
10/10 Excellent
More cheap accommodation in Southern Illinois
Welcome Suites
148 Regency Park O'Fallon IL
The price is AU$76 per night from 24 June to 25 June
AU$76
24 June - 25 June
includes taxes & fees
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